Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Motivation: Protein subcellular localization is crucial for genome annotation, protein function prediction, and drug discovery. However, since determining subcellular localization...
Emily Chia-Yu Su, Hua-Sheng Chiu, Allan Lo, Jenn-K...
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
- The search for structural similarity among proteins can provide valuable insights into their functional mechanisms and their functional relationships. Though the protein 1D seque...
Abstract. An important unsolved problem in structural bioinformatics is that of protein structure prediction (PSP), the reconstruction of a biologically plausible three-dimensional...
Stefano Teso, Cristina Di Risio, Andrea Passerini,...