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BMCBI
2010
97views more  BMCBI 2010»
14 years 10 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
ICLP
2004
Springer
15 years 3 months ago
Protein Folding Simulation in CCP
A protein is identified by a finite sequence of aminoacids, each of them chosen from a set of 20 elements. The Protein Structure Prediction Problem is the problem of predicting t...
Alessandro Dal Palù, Agostino Dovier, Feder...
BMCBI
2008
146views more  BMCBI 2008»
14 years 10 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Rule Clustering and Super-rule Generation for Transmembrane Segments Prediction
The explanation of a decision is important for the acceptance of machine learning technology in bioinformatics applications such as protein structure prediction. In past research,...
Jieyue He, Bernard Chen, Hae-Jin Hu, Robert W. Har...
BIOINFORMATICS
2005
169views more  BIOINFORMATICS 2005»
14 years 9 months ago
A statistical model providing comprehensive predictions for the mRNA differential display
s Dirk Tremmel, Maximilian Tropschug N. crassa FKBP22 is part of a protein folding helper complex in the ER [oral presentation] Manuela Heiner A carbamate-cleaving catalytic antibo...
David Meintrup, Ellen Reisinger