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BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
Identification of biomarkers from mass spectrometry data using a "common" peak approach
Background: Proteomic data obtained from mass spectrometry have attracted great interest for the detection of early-stage cancer. However, as mass spectrometry data are high-dimen...
Tadayoshi Fushiki, Hironori Fujisawa, Shinto Eguch...
BMCBI
2004
151views more  BMCBI 2004»
14 years 9 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BIBE
2010
IEEE
181views Bioinformatics» more  BIBE 2010»
14 years 11 months ago
Multi Level Clustering of Phylogenetic Profiles
The prediction of gene function from genome sequences is one of the main issues in Bioinformatics. Most computational approaches are based on the similarity between sequences to in...
Fotis E. Psomopoulos, Pericles A. Mitkas
BMCBI
2007
102views more  BMCBI 2007»
14 years 10 months ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
ICTAI
2007
IEEE
15 years 4 months ago
A Java-Based Distributed Genetic Algorithm Framework
Distributed Genetic Algorithm (DGA) is one of the most promising choices among the optimization methods. In this paper we describe DGAFrame, a flexible framework for evolutionary...
Gabi Escuela, Yudith Cardinale, Jorge Gonzá...