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» A Web-based requirements analysis tool
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112
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BMCBI
2007
119views more  BMCBI 2007»
15 years 17 days ago
Conceptual-level workflow modeling of scientific experiments using NMR as a case study
Background: Scientific workflows improve the process of scientific experiments by making computations explicit, underscoring data flow, and emphasizing the participation of humans...
Kacy K. Verdi, Heidi J. C. Ellis, Michael R. Gryk
111
Voted
BMCBI
2008
100views more  BMCBI 2008»
15 years 17 days ago
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen p
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
Guanglan Zhang, Asif M. Khan, Kellathur N. Sriniva...
97
Voted
BMCBI
2006
116views more  BMCBI 2006»
15 years 15 days ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
JKM
2006
135views more  JKM 2006»
15 years 13 days ago
Learning from the Mars Rover Mission: scientific discovery, learning and memory
Purpose Knowledge management for space exploration is part of a multi-generational effort. Each mission builds on knowledge from prior missions, and learning is the first step in ...
Charlotte Linde
BMCBI
2005
135views more  BMCBI 2005»
15 years 11 days ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...