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» A boosting approach for motif modeling using ChIP-chip data
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BCBGC
2008
14 years 11 months ago
BMA - Boolean Matrices as Model for Motif Kernels
We introduce the data model BM, which specifies kernels of motifs by means of Boolean matrices. Different from position frequency matrices these only specify which bases can appea...
Jan Schröder, Manfred Schimmler, Heiko Schr&o...
BIOINFORMATICS
2012
13 years 9 days ago
Epigenetic priors for identifying active transcription factor binding sites
Motivation Accurate knowledge of the genome-wide binding of transcription factors in a particular cell type or under a particular condition is necessary for understanding transcri...
Gabriel Cuellar-Partida, Fabian A. Buske, Robert C...
BMCBI
2010
154views more  BMCBI 2010»
14 years 10 months ago
Motif Enrichment Analysis: a unified framework and an evaluation on ChIP data
Background: A major goal of molecular biology is determining the mechanisms that control the transcription of genes. Motif Enrichment Analysis (MEA) seeks to determine which DNA-b...
Robert C. McLeay, Timothy L. Bailey
CIKM
2009
Springer
15 years 4 months ago
Feature selection for ranking using boosted trees
Modern search engines have to be fast to satisfy users, so there are hard back-end latency requirements. The set of features useful for search ranking functions, though, continues...
Feng Pan, Tim Converse, David Ahn, Franco Salvetti...
BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota