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BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
An algorithm for automated closure during assembly
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
97
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TSP
2010
14 years 4 months ago
Variance-component based sparse signal reconstruction and model selection
We propose a variance-component probabilistic model for sparse signal reconstruction and model selection. The measurements follow an underdetermined linear model, where the unknown...
Kun Qiu, Aleksandar Dogandzic
BMCBI
2007
157views more  BMCBI 2007»
14 years 9 months ago
Improving gene set analysis of microarray data by SAM-GS
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
BMCBI
2008
159views more  BMCBI 2008»
14 years 9 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
SAC
2009
ACM
15 years 4 months ago
GTfold: a scalable multicore code for RNA secondary structure prediction
The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...