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ICFP
2010
ACM
15 years 3 months ago
Matching lenses: alignment and view update
Bidirectional programming languages are a practical approach to the view update problem. Programs in these languages, called lenses, define both a view and an update policy--i.e.,...
Davi M. J. Barbosa, Julien Cretin, Nate Foster, Mi...
BMCBI
2010
141views more  BMCBI 2010»
15 years 2 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
BMCBI
2010
153views more  BMCBI 2010»
15 years 2 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2010
115views more  BMCBI 2010»
15 years 2 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2010
147views more  BMCBI 2010»
15 years 2 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...