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» A copula method for modeling directional dependence of genes
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BMCBI
2008
159views more  BMCBI 2008»
14 years 9 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
TCAD
2002
128views more  TCAD 2002»
14 years 9 months ago
Preferred direction Steiner trees
Interconnect optimization for VLSI circuits has received wide attention. To model routing surfaces, multiple circuit layers are freabstracted as a single rectilinear plane, ignori...
Mehmet Can Yildiz, Patrick H. Madden
BMCBI
2008
114views more  BMCBI 2008»
14 years 9 months ago
Dinucleotide controlled null models for comparative RNA gene prediction
Background: Comparative prediction of RNA structures can be used to identify functional noncoding RNAs in genomic screens. It was shown recently by Babak et al. [BMC Bioinformatic...
Tanja Gesell, Stefan Washietl
JMLR
2010
132views more  JMLR 2010»
14 years 4 months ago
Learning Gradients: Predictive Models that Infer Geometry and Statistical Dependence
The problems of dimension reduction and inference of statistical dependence are addressed by the modeling framework of learning gradients. The models we propose hold for Euclidean...
Qiang Wu, Justin Guinney, Mauro Maggioni, Sayan Mu...
RECOMB
2005
Springer
15 years 10 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli