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CIKM
2006
Springer
15 years 1 months ago
Structure-based querying of proteins using wavelets
The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we...
Keith Marsolo, Srinivasan Parthasarathy, Kotagiri ...
NIPS
2003
14 years 11 months ago
Non-linear CCA and PCA by Alignment of Local Models
We propose a non-linear Canonical Correlation Analysis (CCA) method which works by coordinating or aligning mixtures of linear models. In the same way that CCA extends the idea of...
Jakob J. Verbeek, Sam T. Roweis, Nikos A. Vlassis
ICML
2007
IEEE
15 years 10 months ago
Hierarchical Gaussian process latent variable models
The Gaussian process latent variable model (GP-LVM) is a powerful approach for probabilistic modelling of high dimensional data through dimensional reduction. In this paper we ext...
Neil D. Lawrence, Andrew J. Moore
BMCBI
2010
177views more  BMCBI 2010»
14 years 10 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
BMCBI
2007
137views more  BMCBI 2007»
14 years 10 months ago
Bayesian refinement of protein functional site matching
Background: Matching functional sites is a key problem for the understanding of protein function and evolution. The commonly used graph theoretic approach, and other related appro...
Kanti V. Mardia, Vysaul B. Nyirongo, Peter J. Gree...