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GECCO
2009
Springer
15 years 4 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
BMCBI
2006
182views more  BMCBI 2006»
14 years 9 months ago
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
ISVC
2009
Springer
15 years 2 months ago
A 3D Active Surface Model for the Accurate Segmentation of Drosophila Schneider Cell Nuclei and Nucleoli
Abstract. We present an active surface model designed for the segmentation of Drosophila Schneider cell nuclei and nucleoli from wide-field microscopic data. The imaging technique...
Margret Keuper, Jan Padeken, Patrick Heun, Hans Bu...
BMCBI
2005
67views more  BMCBI 2005»
14 years 9 months ago
Sequence signature analysis of chromosome identity in three Drosophila species
Background: All eukaryotic organisms need to distinguish each of their chromosomes. A few protein complexes have been described that recognise entire, specific chromosomes, for in...
Per Stenberg, Fredrik Pettersson, Anja O. Saura, A...
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...