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» A factor analysis model for functional genomics
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BMCBI
2007
149views more  BMCBI 2007»
14 years 9 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
RECOMB
2009
Springer
15 years 10 months ago
Spatial Clustering of Multivariate Genomic and Epigenomic Information
The combination of fully sequence genomes and new technologies for high density arrays and ultra-rapid sequencing enables the mapping of generegulatory and epigenetics marks on a g...
Rami Jaschek, Amos Tanay
DAC
2000
ACM
15 years 10 months ago
On switch factor based analysis of coupled RC interconnects
We revisit a basic element of modern signal integrity analysis, the modeling of worst-case coupling capacitance effects within a switch factor (SF) based methodology. We show that...
Andrew B. Kahng, Sudhakar Muddu, Egino Sarto
BMCBI
2005
86views more  BMCBI 2005»
14 years 9 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
BMCBI
2011
14 years 4 months ago
Predicting functionally important SNP classes based on negative selection
Background: With the advent of cost-effective genotyping technologies, genome-wide association studies allow researchers to examine hundreds of thousands of single nucleotide poly...
Mark A. Levenstien, Robert J. Klein