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» A factor model to analyze heterogeneity in gene expression
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BMCBI
2007
117views more  BMCBI 2007»
14 years 9 months ago
Application of a correlation correction factor in a microarray cross-platform reproducibility study
Background: Recent research examining cross-platform correlation of gene expression intensities has yielded mixed results. In this study, we demonstrate use of a correction factor...
Kellie J. Archer, Catherine I. Dumur, G. Scott Tay...
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
14 years 9 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
NIPS
2008
14 years 11 months ago
A mixture model for the evolution of gene expression in non-homogeneous datasets
We address the challenge of assessing conservation of gene expression in complex, non-homogeneous datasets. Recent studies have demonstrated the success of probabilistic models in...
Gerald Quon, Yee Whye Teh, Esther Chan, Timothy R....
BMCBI
2004
115views more  BMCBI 2004»
14 years 9 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
BMCBI
2006
153views more  BMCBI 2006»
14 years 9 months ago
Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data by using projective adaptive
Background: Recent advances in genome technologies have provided an excellent opportunity to determine the complete biological characteristics of neoplastic tissues, resulting in ...
Hiro Takahashi, Takeshi Nemoto, Teruhiko Yoshida, ...