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» A factor model to analyze heterogeneity in gene expression
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BMCBI
2007
169views more  BMCBI 2007»
14 years 9 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
BMCBI
2005
201views more  BMCBI 2005»
14 years 9 months ago
A comparative study of discriminating human heart failure etiology using gene expression profiles
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
Xiaohong Huang, Wei Pan, Suzanne Grindle, Xinqiang...
BMCBI
2010
91views more  BMCBI 2010»
14 years 8 months ago
Washing scaling of GeneChip microarray expression
Background: Post-hybridization washing is an essential part of microarray experiments. Both the quality of the experimental washing protocol and adequate consideration of washing ...
Hans Binder, Knut Krohn, Conrad J. Burden
RECOMB
2008
Springer
15 years 10 months ago
Accounting for Non-genetic Factors Improves the Power of eQTL Studies
Abstract. The recent availability of large scale data sets profiling single nucleotide polymorphisms (SNPs) and gene expression across different human populations, has directed muc...
Oliver Stegle, Anitha Kannan, Richard Durbin, John...
BMCBI
2006
130views more  BMCBI 2006»
14 years 9 months ago
CARMA: A platform for analyzing microarray datasets that incorporate replicate measures
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
Kevin A. Greer, Matthew R. McReynolds, Heddwen L. ...