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» A factor model to analyze heterogeneity in gene expression
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JCB
2007
145views more  JCB 2007»
14 years 9 months ago
Confounding Factors in HGT Detection: Statistical Error, Coalescent Effects, and Multiple Solutions
Prokaryotic organisms share genetic material across species boundaries by means of a process known as horizontal gene transfer (HGT). This process has great significance for unde...
Cuong Than, Derek A. Ruths, Hideki Innan, Luay Nak...
BMCBI
2007
182views more  BMCBI 2007»
14 years 9 months ago
Additive risk survival model with microarray data
Background: Microarray techniques survey gene expressions on a global scale. Extensive biomedical studies have been designed to discover subsets of genes that are associated with ...
Shuangge Ma, Jian Huang
90
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NAR
2008
142views more  NAR 2008»
14 years 9 months ago
CMGSDB: integrating heterogeneous Caenorhabditis elegans data sources using compositional data mining
CMGSDB (Database for Computational Modeling of Gene Silencing) is an integration of heterogeneous data sources about Caenorhabditis elegans with capabilities for compositional dat...
Amrita Pati, Ying Jin, Karsten Klage, Richard F. H...
BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
RECOMB
2006
Springer
15 years 10 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...