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» A factor model to analyze heterogeneity in gene expression
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IJON
2006
95views more  IJON 2006»
14 years 9 months ago
Generalized relevance LVQ (GRLVQ) with correlation measures for gene expression analysis
A correlation-based similarity measure is derived for generalized relevance learning vector quantization (GRLVQ). The resulting GRLVQ-C classifier makes Pearson correlation availa...
Marc Strickert, Udo Seiffert, Nese Sreenivasulu, W...
ISMB
1997
14 years 11 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
SplicerAV: a tool for mining microarray expression data for changes in RNA processing
Background: Over the past two decades more than fifty thousand unique clinical and biological samples have been assayed using the Affymetrix HG-U133 and HG-U95 GeneChip microarray...
Timothy J. Robinson, Michaela A. Dinan, Mark Dewhi...
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
GOAL: A software tool for assessing biological significance of genes groups
Background: Modern high throughput experimental techniques such as DNA microarrays often result in large lists of genes. Computational biology tools such as clustering are then us...
Alain B. Tchagang, Alexander Gawronski, Hugo B&eac...
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...