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» A factor model to analyze heterogeneity in gene expression
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APBC
2003
120views Bioinformatics» more  APBC 2003»
15 years 2 months ago
From Informatics to Bioinformatics
Informatics has helped in launching molecular biology into the genomic era. It appears certain that informatics will continue to be a major factor in the success of molecular biol...
Vladimir B. Bajic, Vladimir Brusic, Jinyan Li, See...
BMCBI
2006
156views more  BMCBI 2006»
15 years 1 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
CMSB
2004
Springer
15 years 5 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...
IJON
2007
76views more  IJON 2007»
15 years 1 months ago
Modeling L-LTP based on changes in concentration of pCREB transcription factor
We simulate the induction and maintenance of late long-term potentiation (L-LTP) in the hippocampal dentate gyrus by means of a new synaptic plasticity rule that is the result of ...
Lubica Benuskova, Nikola Kasabov
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
15 years 1 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...