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» A factor model to analyze heterogeneity in gene expression
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APBC
2003
120views Bioinformatics» more  APBC 2003»
14 years 11 months ago
From Informatics to Bioinformatics
Informatics has helped in launching molecular biology into the genomic era. It appears certain that informatics will continue to be a major factor in the success of molecular biol...
Vladimir B. Bajic, Vladimir Brusic, Jinyan Li, See...
113
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BMCBI
2006
156views more  BMCBI 2006»
14 years 9 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
CMSB
2004
Springer
15 years 1 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...
IJON
2007
76views more  IJON 2007»
14 years 9 months ago
Modeling L-LTP based on changes in concentration of pCREB transcription factor
We simulate the induction and maintenance of late long-term potentiation (L-LTP) in the hippocampal dentate gyrus by means of a new synaptic plasticity rule that is the result of ...
Lubica Benuskova, Nikola Kasabov
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
14 years 9 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...