Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
A number of diseases, such as arthritis and cardiovascular disorders impacting the lives of many people have strong inflammatory components. To elucidate the antiinflammatory mecha...
Jing Yu, Gabriel Helmlinger, Muriel Saulnier, Anna...
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...
Non-negative matrix factorization (NMF) has become a standard tool in data mining, information retrieval, and signal processing. It is used to factorize a non-negative data matrix ...
C. Thurau, K. Kersting, M. Wahabzada, and C. Bauck...