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» A factor model to analyze heterogeneity in gene expression
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BMCBI
2008
201views more  BMCBI 2008»
14 years 9 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2006
124views more  BMCBI 2006»
14 years 9 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
BMCBI
2010
115views more  BMCBI 2010»
14 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
CVPR
2005
IEEE
15 years 11 months ago
Joint Nonparametric Alignment for Analyzing Spatial Gene Expression Patterns in Drosophila Imaginal Discs
To compare spatial patterns of gene expression, one must analyze a large number of images as current methods are only able to measure a small number of genes at a time. Bringing i...
Parvez Ahammad, Cyrus L. Harmon, Ann Hammonds, Sha...