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» A factor model to analyze heterogeneity in gene expression
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BMCBI
2007
143views more  BMCBI 2007»
14 years 9 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2010
216views more  BMCBI 2010»
14 years 4 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
ICASSP
2011
IEEE
14 years 1 months ago
Uncover cooperative gene regulations by microRNAs and transcription factors in glioblastoma using a nonnegative hybrid factor mo
—Transcriptional regulation by transcription factors (TFs) and microRNAs controls when and how much RNA is created. Due to technical limitations, the protein level expressions of...
Jia Meng, Hung-I Harry Chen, Jianqiu Zhang, Yidong...
ECWEB
2006
Springer
126views ECommerce» more  ECWEB 2006»
15 years 1 months ago
Web User Segmentation Based on a Mixture of Factor Analyzers
Abstract. This paper proposes an approach for Web user segmentation and online behavior analysis based on a mixture of factor analyzers (MFA). In our proposed framework, we model u...
Yanzan Zhou, Bamshad Mobasher
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali