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125
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TKDE
2008
153views more  TKDE 2008»
15 years 18 days ago
Discovering Frequent Agreement Subtrees from Phylogenetic Data
We study a new data mining problem concerning the discovery of frequent agreement subtrees (FASTs) from a set of phylogenetic trees. A phylogenetic tree, or phylogeny, is an unorde...
Sen Zhang, Jason Tsong-Li Wang
104
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BMCBI
2005
158views more  BMCBI 2005»
15 years 18 days ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
144
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BMCBI
2005
113views more  BMCBI 2005»
15 years 18 days ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
102
Voted
TKDE
2008
125views more  TKDE 2008»
15 years 18 days ago
Discovering and Explaining Abnormal Nodes in Semantic Graphs
An important problem in the area of homeland security is to identify abnormal or suspicious entities in large datasets. Although there are methods from data mining and social netwo...
Shou-de Lin, Hans Chalupsky
128
Voted
JCB
2007
198views more  JCB 2007»
15 years 18 days ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
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