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» A framework for modelling virus gene expression data
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BMCBI
2004
150views more  BMCBI 2004»
15 years 25 days ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
BMCBI
2008
140views more  BMCBI 2008»
15 years 1 months ago
GORouter: an RDF model for providing semantic query and inference services for Gene Ontology and its associations
Background: The most renowned biological ontology, Gene Ontology (GO) is widely used for annotations of genes and gene products of different organisms. However, there are shortcom...
Qingwei Xu, Yixiang Shi, Qiang Lu, Guo-qing Zhang,...
BMCBI
2010
152views more  BMCBI 2010»
15 years 1 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
ICANN
2010
Springer
15 years 2 months ago
Discovery of Exogenous Variables in Data with More Variables Than Observations
Many statistical methods have been proposed to estimate causal models in classical situations with fewer variables than observations. However, modern datasets including gene expres...
Yasuhiro Sogawa, Shohei Shimizu, Aapo Hyvärin...
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BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
15 years 1 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...