An optimization query asks for one or more data objects that maximize or minimize some function over the data set. We propose a general class of queries, model-based optimization ...
Background: The increasing availability and diversity of omics data in the post-genomic era offers new perspectives in most areas of biomedical research. Graph-based biological ne...
Alexander Martin, Maria Elena Ochagavia, Laya C. R...
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...
Background: Information resources on the World Wide Web play an indispensable role in modern biology. But integrating data from multiple sources is often encumbered by the need to...
J. Christopher Bare, Paul T. Shannon, Amy K. Schmi...
The problem of overlapping clustering, where a point is allowed to belong to multiple clusters, is becoming increasingly important in a variety of applications. In this paper, we ...