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BMCBI
2007
103views more  BMCBI 2007»
13 years 6 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
JCB
2007
198views more  JCB 2007»
13 years 6 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
SIGMOD
2008
ACM
215views Database» more  SIGMOD 2008»
14 years 6 months ago
CSV: visualizing and mining cohesive subgraphs
Extracting dense sub-components from graphs efficiently is an important objective in a wide range of application domains ranging from social network analysis to biological network...
Nan Wang, Srinivasan Parthasarathy, Kian-Lee Tan, ...

Publication
197views
12 years 2 months ago
Convex non-negative matrix factorization for massive datasets
Non-negative matrix factorization (NMF) has become a standard tool in data mining, information retrieval, and signal processing. It is used to factorize a non-negative data matrix ...
C. Thurau, K. Kersting, M. Wahabzada, and C. Bauck...
BMCBI
2005
169views more  BMCBI 2005»
13 years 6 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...