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» A genome alignment algorithm based on compression
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BMCBI
2006
137views more  BMCBI 2006»
14 years 9 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assess
Background: Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. Howeve...
Paolo Ferragina, Raffaele Giancarlo, Valentina Gre...
RECOMB
2008
Springer
15 years 9 months ago
A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery
As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. M...
Raluca Gordân, Leelavati Narlikar, Alexander...
JCB
2007
107views more  JCB 2007»
14 years 9 months ago
Effects of Long-Range Correlations in DNA on Sequence Alignment Score Statistics
Long-range correlations in genomic base composition are a ubiquitous statistical feature among many eukaryotic genomes. In this article, these correlations are shown to substantia...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
BMCBI
2008
146views more  BMCBI 2008»
14 years 9 months ago
nGASP - the nematode genome annotation assessment project
Background: While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation asses...
Avril Coghlan, Tristan J. Fiedler, Sheldon J. McKa...