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» A geometric database for gene expression data
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BMCBI
2004
131views more  BMCBI 2004»
15 years 1 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
PVLDB
2008
111views more  PVLDB 2008»
15 years 1 months ago
Approximate lineage for probabilistic databases
In probabilistic databases, lineage is fundamental to both query processing and understanding the data. Current systems s.a. Trio or Mystiq use a complete approach in which the li...
Christopher Ré, Dan Suciu
BMCBI
2006
133views more  BMCBI 2006»
15 years 1 months ago
Web-based analysis of the mouse transcriptome using Genevestigator
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...
BMCBI
2007
159views more  BMCBI 2007»
15 years 1 months ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...
BMCBI
2007
120views more  BMCBI 2007»
15 years 1 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...