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» A hybrid genetic search for multiple sequence alignment
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BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
14 years 9 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BMCBI
2010
155views more  BMCBI 2010»
14 years 7 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2007
164views more  BMCBI 2007»
14 years 9 months ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason
CORR
2008
Springer
71views Education» more  CORR 2008»
14 years 9 months ago
Problem Solving and Complex Systems
The observation and modeling of natural Complex Systems (CSs) like the human nervous system, the evolution or the weather, allows the definition of special abilities and models re...
Frédéric Guinand, Yoann Pigné
74
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EMO
2006
Springer
117views Optimization» more  EMO 2006»
14 years 11 months ago
Multiplex PCR Assay Design by Hybrid Multiobjective Evolutionary Algorithm
Abstract. Multiplex Polymerase Chain Reaction (PCR) assay is to amplify multiple target DNAs simultaneously using different primer pairs for each target DNA. Recently, it is widely...
In-Hee Lee, Soo-Yong Shin, Byoung-Tak Zhang