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» A hybrid genetic search for multiple sequence alignment
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BMCBI
2006
122views more  BMCBI 2006»
14 years 9 months ago
CoSMoS: Conserved Sequence Motif Search in the proteome
Background: With the ever-increasing number of gene sequences in the public databases, generating and analyzing multiple sequence alignments becomes increasingly time consuming. N...
Xiao I. Liu, Neeraj Korde, Ursula Jakob, Lars I. L...
BMCBI
2010
147views more  BMCBI 2010»
14 years 9 months ago
Automatic detection of anchor points for multiple sequence alignment
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
Florian Pitschi, Claudine Devauchelle, Eduardo Cor...
89
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ICIC
2009
Springer
15 years 4 months ago
A Method for Multiple Sequence Alignment Based on Particle Swarm Optimization
Sequence Alignment is a basic information disposal method in Bioinformatics. However, it is difficult to deal with multiple sequence alignment problem(MSA). In this paper, an impro...
Fasheng Xu, Yuehui Chen
NAR
2008
152views more  NAR 2008»
14 years 9 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
NAR
1998
86views more  NAR 1998»
14 years 9 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...