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» A hybrid genetic search for multiple sequence alignment
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BMCBI
2008
123views more  BMCBI 2008»
14 years 9 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
DEXA
2007
Springer
150views Database» more  DEXA 2007»
15 years 3 months ago
Sequence Alignment as a Database Technology Challenge
Abstract. Sequence alignment is an important task for molecular biologists. Because alignment basically deals with approximate string matching on large biological sequence collecti...
Hans Philippi
GECCO
2006
Springer
159views Optimization» more  GECCO 2006»
15 years 1 months ago
Identification of weak motifs in multiple biological sequences using genetic algorithm
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Topon Kumar Paul, Hitoshi Iba
AIPS
2008
14 years 12 months ago
A New Hybrid Genetic Algorithm for the Job Shop Scheduling Problem with Setup Times
In this paper we face the Job Shop Scheduling Problem with Sequence Dependent Setup Times by means of a genetic algorithm hybridized with local search. We have built on a previous...
Miguel A. González, Camino R. Vela, Ramiro ...
GECCO
2007
Springer
258views Optimization» more  GECCO 2007»
15 years 1 months ago
TFBS identification by position- and consensus-led genetic algorithm with local filtering
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Tak-Ming Chan, Kwong-Sak Leung, Kin-Hong Lee