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BMCBI
2008
95views more  BMCBI 2008»
14 years 9 months ago
Mining protein networks for synthetic genetic interactions
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...
Sri R. Paladugu, Shan Zhao, Animesh Ray, Alpan Rav...
BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
MSR
2010
ACM
15 years 2 months ago
Validity of network analyses in Open Source Projects
—Social network methods are frequently used to analyze networks derived from Open Source Project communication and collaboration data. Such studies typically discover patterns in...
Roozbeh Nia, Christian Bird, Premkumar T. Devanbu,...
BMCBI
2008
123views more  BMCBI 2008»
14 years 9 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
BMCBI
2005
80views more  BMCBI 2005»
14 years 9 months ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...