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113
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RECOMB
2006
Springer
16 years 1 months ago
Identification and Evaluation of Functional Modules in Gene Co-expression Networks
Abstract. Identifying gene functional modules is an important step towards elucidating gene functions at a global scale. In this paper, we introduce a simple method to construct ge...
Jianhua Ruan, Weixiong Zhang
CVPR
2008
IEEE
16 years 2 months ago
Constrained spectral clustering through affinity propagation
Pairwise constraints specify whether or not two samples should be in one cluster. Although it has been successful to incorporate them into traditional clustering methods, such as ...
Miguel Á. Carreira-Perpiñán, ...
JBI
2004
171views Bioinformatics» more  JBI 2004»
15 years 2 months ago
Consensus Clustering and Functional Interpretation of Gene Expression Data
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters. Obtaining a consensus s...
Paul Kellam, Stephen Swift, Allan Tucker, Veronica...
110
Voted
BMCBI
2010
115views more  BMCBI 2010»
15 years 24 days ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
103
Voted
BMCBI
2007
134views more  BMCBI 2007»
15 years 24 days ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...