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» A new approach to analyzing gene expression time series data
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BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Efficient genome-scale phylogenetic analysis under the duplication-loss and deep coalescence cost models
Background: Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extr...
Mukul S. Bansal, J. Gordon Burleigh, Oliver Eulens...
CGF
2010
146views more  CGF 2010»
14 years 10 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...
BMCBI
2007
133views more  BMCBI 2007»
14 years 10 months ago
GenMAPP 2: new features and resources for pathway analysis
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
Nathan Salomonis, Kristina Hanspers, Alexander C. ...
BIBE
2008
IEEE
137views Bioinformatics» more  BIBE 2008»
15 years 4 months ago
A sparse variational Bayesian approach for fMRI data analysis
— The aim of this work is to propose a new approach for the determination of the design matrix in fMRI experiments. The design matrix embodies all available knowledge about exper...
Vangelis P. Oikonomou, Evanthia E. Tripoliti, Dimi...