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» A new evolutionary model for detecting multiple optima
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99
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BMCBI
2008
147views more  BMCBI 2008»
14 years 9 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2008
148views more  BMCBI 2008»
14 years 9 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
IPPS
2009
IEEE
15 years 4 months ago
Exploring FPGAs for accelerating the phylogenetic likelihood function
Driven by novel biological wet lab techniques such as pyrosequencing there has been an unprecedented molecular data explosion over the last 2-3 years. The growth of biological seq...
Nikolaos Alachiotis, Euripides Sotiriades, Apostol...
95
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MANSCI
2007
90views more  MANSCI 2007»
14 years 9 months ago
Selecting a Selection Procedure
Selection procedures are used in a variety of applications to select the best of a finite set of alternatives. ‘Best’ is defined with respect to the largest mean, but the me...
Jürgen Branke, Stephen E. Chick, Christian Sc...