Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Driven by novel biological wet lab techniques such as pyrosequencing there has been an unprecedented molecular data explosion over the last 2-3 years. The growth of biological seq...
Selection procedures are used in a variety of applications to select the best of a finite set of alternatives. ‘Best’ is defined with respect to the largest mean, but the me...