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GECCO
2006
Springer
220views Optimization» more  GECCO 2006»
13 years 10 months ago
Comparing evolutionary algorithms on the problem of network inference
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of different evoluti...
Christian Spieth, Rene Worzischek, Felix Streicher...
BMCBI
2010
129views more  BMCBI 2010»
13 years 6 months ago
Geoseq: a tool for dissecting deep-sequencing datasets
Background: Datasets generated on deep-sequencing platforms have been deposited in various public repositories such as the Gene Expression Omnibus (GEO), Sequence Read Archive (SR...
James Gurtowski, Anthony Cancio, Hardik Shah, Chay...
BMCBI
2005
124views more  BMCBI 2005»
13 years 6 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2008
108views more  BMCBI 2008»
13 years 6 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...
BMCBI
2010
136views more  BMCBI 2010»
13 years 6 months ago
Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
Russell L. Zaretzki, Michael A. Gilchrist, William...