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BMCBI
2010
131views more  BMCBI 2010»
13 years 6 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
BMCBI
2005
153views more  BMCBI 2005»
13 years 6 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...
BMCBI
2007
156views more  BMCBI 2007»
13 years 6 months ago
Large-scale clustering of CAGE tag expression data
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
Kazuro Shimokawa, Yuko Okamura-Oho, Takio Kurita, ...
BMCBI
2008
126views more  BMCBI 2008»
13 years 6 months ago
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
Anne M. Denton, Jianfei Wu, Megan K. Townsend, Pre...
BMCBI
2002
147views more  BMCBI 2002»
13 years 6 months ago
Expression profiling of human renal carcinomas with functional taxonomic analysis
Background: Molecular characterization has contributed to the understanding of the inception, progression, treatment and prognosis of cancer. Nucleic acid array-based technologies...
Michael A. Gieseg, Theresa Cody, Michael Z. Man, S...