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» A polyhedral approach to sequence alignment problems
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COMPLIFE
2005
Springer
15 years 3 months ago
Fast and Accurate Structural RNA Alignment by Progressive Lagrangian Optimization
During the last few years new functionalities of RNA have been discovered, renewing the need for computational tools for their analysis. To this respect, multiple sequence alignmen...
Markus Bauer, Gunnar W. Klau, Knut Reinert
BMCBI
2005
162views more  BMCBI 2005»
14 years 9 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
93
Voted
GCB
2000
Springer
137views Biometrics» more  GCB 2000»
15 years 1 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
BIOCOMP
2007
14 years 11 months ago
Quality-Based Similarity Search for Biological Sequence Databases
Low-Complexity Regions (LCRs) of biological sequences are the main source of false positives in similarity searches for biological sequence databases. We consider the problem of ï...
Xuehui Li, Tamer Kahveci
BMCBI
2006
159views more  BMCBI 2006»
14 years 9 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...