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» A polyhedral approach to sequence alignment problems
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BMCBI
2006
125views more  BMCBI 2006»
14 years 9 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
BMCBI
2007
113views more  BMCBI 2007»
14 years 9 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BMCBI
2005
119views more  BMCBI 2005»
14 years 9 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
166
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ICDE
2006
IEEE
188views Database» more  ICDE 2006»
15 years 11 months ago
Efficiently Evaluating Order Preserving Similarity Queries over Historical Market-Basket Data
We introduce a new domain-independent framework for formulating and efficiently evaluating similarity queries over historical data, where given a history as a sequence of timestam...
Reza Sherkat, Davood Rafiei
CCGRID
2003
IEEE
15 years 2 months ago
A Parallel FPT Application For Clusters
Fixed-parameter tractability (FPT) techniques have recently been successful in solving NP-complete problem instances of practical importance which were too large to be solved with...
James Cheetham, Frank K. H. A. Dehne, Andrew Rau-C...