Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
We introduce a new domain-independent framework for formulating and efficiently evaluating similarity queries over historical data, where given a history as a sequence of timestam...
Fixed-parameter tractability (FPT) techniques have recently been successful in solving NP-complete problem instances of practical importance which were too large to be solved with...
James Cheetham, Frank K. H. A. Dehne, Andrew Rau-C...