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» A protein interaction based model for schizophrenia study
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NIPS
2004
15 years 1 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
ICCS
2007
Springer
15 years 5 months ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
BMCBI
2007
101views more  BMCBI 2007»
14 years 11 months ago
Relationship between insertion/deletion (indel) frequency of proteins and essentiality
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
Simon K. Chan, Michael Hsing, Fereydoun Hormozdiar...
PR
2006
84views more  PR 2006»
14 years 11 months ago
Clustering techniques for protein surfaces
Though most approaches to protein comparison are based on their structure, several studies produced evidence of a strict correlation between the surface characteristics of protein...
Lorenzo Baldacci, Matteo Golfarelli, Alessandra Lu...
86
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BMCBI
2008
121views more  BMCBI 2008»
14 years 11 months ago
iRefIndex: A consolidated protein interaction database with provenance
Background: Interaction data for a given protein may be spread across multiple databases. We set out to create a unifying index that would facilitate searching for these data and ...
Sabry Razick, George Magklaras, Ian M. Donaldson