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ENTCS
2006
128views more  ENTCS 2006»
15 years 1 months ago
Web Verification: Perspective and Challenges
The Web poses novel and interesting problems for both programming language design and verification--and their intersection. This paper provides a personal outline of one thread of...
Shriram Krishnamurthi
BMCBI
2005
124views more  BMCBI 2005»
15 years 1 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
110
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BMCBI
2005
169views more  BMCBI 2005»
15 years 1 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
BMCBI
2004
177views more  BMCBI 2004»
15 years 1 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
126
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BMCBI
2004
132views more  BMCBI 2004»
15 years 1 months ago
Two-stage normalization using background intensities in cDNA microarray data
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
Dankyu Yoon, Sung-Gon Yi, Ju-Han Kim, Taesung Park