42 search results - page 3 / 9 » A search algorithm for fixed-composition protein design |
NIPS
2004
15 years 1 months ago
2004
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
113
Voted
ICCAD
2009
IEEE
14 years 9 months ago
2009
IEEE
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
118
click to vote
BMCBI
2007
14 years 11 months ago
2007
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
BMCBI
2010
14 years 11 months ago
2010
Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subc...
BMCBI
2010
14 years 11 months ago
2010
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...