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BMCBI
2010
98views more  BMCBI 2010»
14 years 10 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
BMCBI
2006
165views more  BMCBI 2006»
14 years 10 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...
ROCAI
2004
Springer
15 years 3 months ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
115
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ICCS
2009
Springer
14 years 8 months ago
A Population-Based Approach for Diversified Protein Loop Structure Sampling
Protein loop structure modeling is regarded as a mini protein folding problem with significant scientific importance. Efficiently sampling the loop conformation space is a key step...
Yaohang Li
BMCBI
2006
116views more  BMCBI 2006»
14 years 10 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...