Abstract: Interoperability for information systems remains a challenge both at the semantic and organisational levels. The original three-level architecture for local databases nee...
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Background: Once specific genes are identified through high throughput genomics technologies there is a need to sort the final gene list to a manageable size for validation studie...
Guohui Zhou, Xinyu Wen, Hang Liu, Michael J. Schli...
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...