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BMCBI
2006
108views more  BMCBI 2006»
15 years 4 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2006
126views more  BMCBI 2006»
15 years 4 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
151views more  BMCBI 2006»
15 years 4 months ago
Machine learning and word sense disambiguation in the biomedical domain: design and evaluation issues
Background: Word sense disambiguation (WSD) is critical in the biomedical domain for improving the precision of natural language processing (NLP), text mining, and information ret...
Hua Xu, Marianthi Markatou, Rositsa Dimova, Hongfa...
BMCBI
2006
112views more  BMCBI 2006»
15 years 4 months ago
A correlated motif approach for finding short linear motifs from protein interaction networks
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
CORR
2006
Springer
125views Education» more  CORR 2006»
15 years 4 months ago
Barriers and local minima in energy landscapes of stochastic local search
: A local search algorithm operating on an instance of a Boolean constraint satisfaction problem (in particular, k-SAT) can be viewed as a stochastic process traversing successive ...
Petteri Kaski
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