4 search results - page 1 / 1 » A simple and robust method for connecting small-molecule dru... |
57
Voted
BMCBI
2008
15 years 21 days ago
2008
Background: Interaction of a drug or chemical with a biological system can result in a geneexpression profile or signature characteristic of the event. Using a suitably robust alg...
111
Voted
ESANN
2008
15 years 2 months ago
2008
Our goal is proposing an unbiased framework for gene expression analysis based on variable selection combined with a significance assessment step. We start by discussing the need ...
100
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RECOMB
2008
Springer
16 years 27 days ago
2008
Springer
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
112
Voted
BMCBI
2010
15 years 21 days ago
2010
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...