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» A statistical approach for array CGH data analysis
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BMCBI
2005
104views more  BMCBI 2005»
14 years 10 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
CDC
2008
IEEE
157views Control Systems» more  CDC 2008»
14 years 10 months ago
A hidden Markov filtering approach to multiple change-point models
We describe a hidden Markov modeling approach to multiple change-points that has attractive computational and statistical properties. This approach yields explicit recursive filter...
Tze Leung Lai, Haipeng Xing
BMCBI
2007
180views more  BMCBI 2007»
14 years 10 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
75
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BMCBI
2010
101views more  BMCBI 2010»
14 years 10 months ago
Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
Zhengdong D. Zhang, Mark B. Gerstein
98
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BIBE
2007
IEEE
133views Bioinformatics» more  BIBE 2007»
15 years 4 months ago
Denoising of Array-Based DNA Copy Number Data Using The Dual-tree Complex Wavelet Transform
—Array-based comparative genomic hybridization (array CGH) is a highly efficient technique, allowing the simultaneous measurement of genomic DNA copy number at hundreds or thous...
Nha Nguyen, Heng Huang, Soontorn Oraintara, Yuhang...