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» A statistical approach for array CGH data analysis
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BMCBI
2010
165views more  BMCBI 2010»
15 years 2 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
BMCBI
2008
129views more  BMCBI 2008»
15 years 2 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2006
142views more  BMCBI 2006»
15 years 2 months ago
PedGenie: an analysis approach for genetic association testing in extended pedigrees and genealogies of arbitrary size
Background: We present a general approach to perform association analyses in pedigrees of arbitrary size and structure, which also allows for a mixture of pedigree members and ind...
Kristina Allen-Brady, Jathine Wong, Nicola J. Camp
CORR
2010
Springer
108views Education» more  CORR 2010»
15 years 2 months ago
Mining The Successful Binary Combinations: Methodology and A Simple Case Study
The importance of finding the characteristics leading to either a success or a failure is one of the driving forces of data mining. The various application areas of finding succes...
Yuval Cohen
BIB
2010
89views more  BIB 2010»
15 years 27 days ago
Knowledge-based data analysis comes of age
The emergence of high-throughput technologies for measuring biological systems has introduced problems for data interpretation that must be addressed for proper inference. First, ...
Michael F. Ochs