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» A stochastic particle-based biological system simulator
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CCE
2005
14 years 9 months ago
Numerical simulation of stochastic gene circuits
Armed with increasingly fast supercomputers and greater knowledge of the molecular mechanisms of gene expression, it is now practical to numerically simulate complex networks of r...
Howard Salis, Yiannis N. Kaznessis
BIOCOMP
2010
14 years 7 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
102
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CMSB
2009
Springer
15 years 4 months ago
A Bayesian Approach to Model Checking Biological Systems
Recently, there has been considerable interest in the use of Model Checking for Systems Biology. Unfortunately, the state space of stochastic biological models is often too large f...
Sumit Kumar Jha, Edmund M. Clarke, Christopher Jam...
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
14 years 10 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
ACSD
2008
IEEE
130views Hardware» more  ACSD 2008»
15 years 4 months ago
BAM: BioAmbient machine
In recent years it has become clear that techniques developed for concurrent programming are in fact very useful for the analysis of complex systems in biology. To some level of i...
Vinod A. Muganthan, Andrew Phillips, Maria Grazia ...