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» A structural EM algorithm for phylogenetic inference
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BMCBI
2006
129views more  BMCBI 2006»
14 years 11 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2006
159views more  BMCBI 2006»
14 years 11 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
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BMCBI
2008
145views more  BMCBI 2008»
14 years 11 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
PKDD
2005
Springer
122views Data Mining» more  PKDD 2005»
15 years 5 months ago
A Probabilistic Clustering-Projection Model for Discrete Data
For discrete co-occurrence data like documents and words, calculating optimal projections and clustering are two different but related tasks. The goal of projection is to find a ...
Shipeng Yu, Kai Yu, Volker Tresp, Hans-Peter Krieg...
ICDM
2007
IEEE
289views Data Mining» more  ICDM 2007»
15 years 6 months ago
Latent Dirichlet Conditional Naive-Bayes Models
In spite of the popularity of probabilistic mixture models for latent structure discovery from data, mixture models do not have a natural mechanism for handling sparsity, where ea...
Arindam Banerjee, Hanhuai Shan