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» A structural alignment kernel for protein structures
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BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
ICIP
2002
IEEE
15 years 11 months ago
Retrieval of 3D protein structures
A protein molecule is made of a long chain of amino acid sequences that fold into a complex three-dimensional structure. It is often the geometrical shapes that determine the prot...
Shann-Ching Chen, Tsuhan Chen
81
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BMCBI
2010
123views more  BMCBI 2010»
14 years 9 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
NAR
2006
164views more  NAR 2006»
14 years 9 months ago
FISH - family identification of sequence homologues using structure anchored hidden Markov models
The FISH server is highly accurate in identifying the family membership of domains in a query protein sequence, even in the case of very low sequence identities to known homologue...
Jeanette Tångrot, Lixiao Wang, Bo Kågs...
BMCBI
2004
77views more  BMCBI 2004»
14 years 9 months ago
A structural study for the optimisation of functional motifs encoded in protein sequences
Background: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that
Allegra Via, Manuela Helmer-Citterich