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» A structural alignment kernel for protein structures
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BMCBI
2004
208views more  BMCBI 2004»
14 years 9 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
NAR
2008
119views more  NAR 2008»
14 years 9 months ago
MALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, ...
Hua Cheng, Bong-Hyun Kim, Nick V. Grishin
NAR
2000
109views more  NAR 2000»
14 years 9 months ago
The ASTRAL compendium for protein structure and sequence analysis
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included...
Steven E. Brenner, Patrice Koehl, Michael Levitt
FGCS
2007
107views more  FGCS 2007»
14 years 9 months ago
Algorithmic re-structuring and data replication for protein structure comparison on a GRID
This paper describes a major restructuring of PROuST, a method for protein structure comparison, for an efficient porting to the Grid. PROuST consists of different components: an...
Giovanni Ciriello, M. Comin, Concettina Guerra
GCB
2009
Springer
139views Biometrics» more  GCB 2009»
15 years 1 months ago
Graph-Kernels for the Comparative Analysis of Protein Active Sites
Abstract: Graphs are often used to describe and analyze the geometry and physicochemical composition of biomolecular structures, such as chemical compounds and protein active sites...
Thomas Fober, Marco Mernberger, Ralph Moritz, Eyke...