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» A structural alignment kernel for protein structures
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BMCBI
2011
14 years 1 months ago
HomPPI: A Class of Sequence Homology Based Protein-Protein Interface Prediction Methods
Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
Li C. Xue, Drena Dobbs, Vasant Honavar
EVOW
2010
Springer
15 years 29 days ago
Improving Multi-Relief for Detecting Specificity Residues from Multiple Sequence Alignments
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
Elena Marchiori
JAIR
2010
132views more  JAIR 2010»
14 years 8 months ago
Using Local Alignments for Relation Recognition
This paper discusses the problem of marrying structural similarity with semantic relatedness for Information Extraction from text. Aiming at accurate recognition of relations, we ...
Sophia Katrenko, Pieter W. Adriaans, Maarten van S...
BMCBI
2008
123views more  BMCBI 2008»
14 years 9 months ago
A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
BMCBI
2004
158views more  BMCBI 2004»
14 years 9 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...